| 释义 |
Russell body Path.|ˈrʌsəl|
[Named after William Russell (1852–1940), Scottish pathologist, who described it in 1890 (Brit. Med. Jrnl. 13 Dec. 1356–60).]
A hyaline mass of immunoglobulin produced in numbers in, and sometimes extruded by, plasma cells in excessive response to challenge by antibodies.
1913O. C. Gruner Biol. of Blood-Cells vi. 276 The intracellular Russell bodies are considered the result of myelin degeneration of the cell-substance. 1970Passmore & Robson Compan. Med. Stud. II. xxv. 39/2 Sometimes the fabrication of antibody within plasma cells is so excessive that hyaline masses of protein (Russell bodies) are deposited in their cytoplasm. 1977R. B. Thompson Disorders of Blood xxxii. 508/2 Occasionally Russell bodies are present... They are intra⁓cellular acidophil hyaline bodies which can be produced in animal cells by injections of bacteria and can be found in many organs and tissues. |