| 释义 |
rifamycin Pharm.|riːfəˈmaɪsɪn|
orig. rifomycin.
[Prob. f. It. rifo-rmare to reform + -mycin.]
Any of a class of natural and semi-synthetic antibiotics of which the first examples were isolated from the fungus Streptomyces mediterranei.
1959P. Sensi et al. in Farmaco (Ed. Sci.) XIV. 146 The antibiotic, named by us rifomycin, shows a high activity against gram-positive bacteria and mycobacteria. 1960Antibiotics Ann. 1959–1960 262 Rifomycin has been isolated in our laboratories from the fermentation broths of a strain of Streptomyces mediterranei. 1963Antibiotics & Chemotherapy XI. 61 The Rifamycins constitute a group of antibiotics, produced by a new Streptomyces. 1970New Scientist 24 Dec. 546/1 Rifamycin B per se is not active against bacteria but slowly degrades in aqueous solution to yield an active product, rifamycin SV. 1976Lancet 11 Dec. 1304/2 The rifamycin antibiotics have been used in the treatment of leprosy since 1963. |