释义 |
rheumatoid, a.|ˈruːmətɔɪd| [f. Gr. ῥευµατ-, ῥεῦµα rheum1 + -oid.] Having the characters of rheumatism; suffering from rheumatism. Also, of or pertaining to rheumatoid arthritis. Chiefly in rheumatoid arthritis, a chronic disease of the joints characterized by changes in the synovial membranes, etc., and resulting in deformity and immobility. rheumatoid factor, any of a group of substances in the blood which are present in increased amounts in persons with rheumatoid arthritis.
1859A. B. Garrod Gout xv. 534 Although unwilling to add to the number of names, I cannot help expressing a desire that one might be found for this disease, not implying any necessary relation between it and either gout or rheumatism. Perhaps Rheumatoid Arthritis would answer the object. 1866Tanner Index of Diseases 233 Rheumatoid Arthritis... Synon. Rheumatic Gout; Chronic Rheumatic Arthritis. 1871Practitioner VII. 87 The judicious practitioner will regulate the action of the bowels of his rheumatoid patient by proper diet. 1876Bartholow Mat. Med. (1879) 224 The joints become the seat of rheumatoid pain. 1949R. M. Pike et al. in Jrnl. Immunol. LXIII. 447 The property of agglutinating sensitized sheep cells to a marked degree appears to be associated almost exclusively with the serum in rheumatoid arthritis. The phenomenon is due to a factor which is present in the serum-globulins and its effect is not diminished on storage for considerable periods. Until this factor is more completely characterized, it may be conveniently termed the ‘rheumatoid factor’. 1950Sci. News XV. 134 The adrenal cortex may play an important role in the pathogenesis of rheumatic and rheumatoid conditions in man. 1956Proc. Soc. Exper. Biol. & Med. XCII. 198/2 Sensitized cells which were strongly agglutinated by the rheumatoid serum. 1957Proc. R. Soc. Med. L. 47 The appearance in the serum of rheumatoid arthritics of a factor similar to those induced in the rabbit sera..suggests that it, too, is an antibody to the non-specific groups of immune γ-globulin. 1957Ann. Rheumatic Dis. XVI. 448/1 The term ‘rheumatoid factor’ (R.F.) has been applied to the substance or substances in the serum of most individuals having rheumatoid arthritis which combines with immune globulins or substances closely associated with immune globulins. 1970Passmore & Robson Compan. Med. Stud. II. xxx. 9/2 This mode of origin was suggested for rheumatoid arthritis; in this disease numerous features..combine to support the idea that this is a ‘disorder of the immunological mechanism’ or even an autoimmune disease... Today there is more support for the alternative hypothesis that rheumatoid arthritis..may be caused by an exogenous agent like a virus or bacterium. 1980Sci. Amer. July 42/2 Among the commonest autoantibodies in man are ‘rheumatoid factors’, a group of antibodies directed against gamma globulin. So rheumaˈtoidal a., rheumaˈtoidally adv.
1889Lancet 9 Nov. 947/2 Repeated rheumatic attacks may beget a condition commonly called rheumatoidal. Ibid., It is of such sufferers that we constantly ask ourselves..is this case going off rheumatoidally? |