| 释义 |
pregnane Chem.|ˈprɛgneɪn|
[ad. G. pregnan (A. Butenandt 1930, in Ber. d. Deut. Chem. Ges. LXIII. 660), f. pregnan-diol pregnanediol (cf. -ane).]
A synthetic, crystalline, saturated, tetracyclic hydrocarbon, C21H36, which has two stereoisomeric forms and from which a group of steroids, including progesterone and pregnanediol, is formally derived; spec. the 5β-isomer.
1932Ann. Rep. Progr. Chem. XXVIII. 237 On oxidation there was formed the saturated diketone, C21H32O2, pregnandione, and by Clemmensen reduction of the latter A. Butenandt, F. Hildebrandt, and H. Brücher have obtained the corresponding hydrocarbon, C21H36, pregnane. 1936Zeitschr. für Kristallogr. XCIII. 478 Pregnane forms platy crystals elongated along the b axis and showing generally the c face only. 1959I. L. Finar Org. Chem. (ed. 2) II. xi. 456 The molecular rotation of any steroid is considered as the sum of the rotation of the fundamental structure (which is the parent hydrocarbon cholestane, androstane, or pregnane) and the rotations contributed by the functional groups. 1960L. T. Samuels in D. M. Greenberg Metabolic Pathways I. xi. 432 The two 21-carbon compounds are 5α-pregnane (allopregnane)..and 5β-pregnane (pregnane). 1971M. F. Mallette et al. Introd. Biochem. xx. 778 Steroids are named as derivatives of the polycyclic hydrocarbons gonane, estrane, androstane, and pregnane. |