| 释义 |
polypharmacy Med.|pɒlɪˈfɑːməsɪ|
[= F. polypharmacie: see poly- and pharmacy; cf. Gr. πολυϕάρµακ-ος knowing or characterized by many drugs or poisons.]
The use of many drugs or medicines in the treatment of disease. Freq. with the suggestion of indiscriminate, unscientific, or excessive prescription.
1762Gentl. Mag. 214 Polypharmacy was never carried to a greater excess. 1832Sir W. Hamilton Discuss. (1852) 253 The murderous polypharmacy of the Solidists. 1904J. F. Payne Eng. Med. Anglo-Sax. T. 148 The profuse polypharmacy of the old Anglo-Saxon leechdoms. 1906H. Sainsbury Principia Therapeutica vi. 109 The purist..whilst limiting himself scrupulously to the use of one drug at a time, will seldom hesitate to prescribe the crude drugs,—opium, digitalis, bark, [etc.]..entirely oblivious of the fact that in so doing he is guilty of the most flagrant polypharmacy. 1928Solis-Cohen & Githens Pharmacotherapeutics v. 379 There is a tendency at the present time to decry the association of remedies as ‘polypharmacy’, and to advocate the use of ‘single medicines’. 1953J. L. Simonsen Plant Products & Utilisation (Univ. Nottingham: Sir Jesse Boot Found. Lect.) 4 There is less polypharmacy now than formerly, but I am satisfied that there is less good prescribing now than in my student days. 1977Lancet 26 Mar. 685/2 Therapeutic misadventures..are more likely in the elderly because of inappropriate dosage,..erratic pill-taking, and polypharmacy for multiple diseases.
So polyˈpharmacal a., ‘that hath many medicines’ (Blount Glossogr. 1656); polyˈpharmacist |-sɪst|, one who practises polypharmacy.
1886W. T. Gairdner in Life Sir R. Christison II. vii. 134 Dr. Graham, a strong and unhesitating therapeutist, and also not a little of a polypharmacist. 1927C. H. La Wall 4,000 Yrs. Pharmacy iii. 93 The Arabians perpetuated the polypharmacal combinations which had come down from the Egyptians. 1966G. Watson Theriac & Mithridatium iii. 114 Texts of ancient medical writers with polypharmacal formulae had become available. |