| 释义 |
pipradrol Pharm.|ˈpɪprədrɒl|
Also (erron.) pipradol.
[f. piperidine + -a- + benzhy)drol s.v. benzo-.]
A colourless crystalline solid, α,α-diphenyl-α-piperid-2-ylmethanol hydrochloride, C18H21NO.HCl, which is used as an antidepressant. Also called pipradrol hydrochloride.
1955Science 11 Feb. 209/2 Meratran is the trademark of the Wm. S. Merrell Co., for its brand of pipradrol. 1955Sci. News Let. 13 Aug. 105/1 The drug is a pipradol chemical trade-named Frenquel by the manufacturer, the Wm. S. Merrell Co. of Cincinnati. 1956Jrnl. Amer. Med. Assoc. 4 Feb. 390/1 Pipradrol hydrochloride is a central nervous system stimulant chemically unrelated to the sympathomimetic amines but exhibiting some of the pharmacological actions of amphetamine. 1962F. C. Ferguson Drug Therapy xxiv. 216 Other types of anti⁓depressants include piperidines; methylphenidate (Ritalin) and pipradrol (Meratran). 1973Approved Names 1973 (Brit. Pharmacopœia Comm.) 59 Pipradol. 1974Ibid. Suppl. 111, For ‘Pipradol’ read ‘Pipradrol’. 1974Jrnl. Clin. Pharmacol. XIV. 132/2 Present results thus suggest at the most only limited efficacy for pipradrol in the treatment of depressed outpatients. |