释义 |
phosphorylase Biochem.|fɒsˈfɒrɪleɪz, -s, ˈfɒsfərɪleɪz, -s| [f. prec. + -ase.] An enzyme that introduces a phosphate group into an organic compound.
1939G. T. Cori et al. in Jrnl. Biol. Chem. CXXVII. 771 Various mammalian tissues..contain an enzyme which can be extracted with water and which forms glucose-1-phosphoric ester..from glycogen and inorganic phosphate... This enzyme, which will be referred to as phosphorylase, initiates the degradation of glycogen. 1955Sci. News Let. 7 May 297/1 Use of muscle to do work and its recovery depends upon the chemical action of an enzyme, phosphorylase, which is found in muscle. 1970[see phosphorolysis]. 1971Nature 19 Feb. 529/1 The breakdown of glycogen, in accordance with instantaneous energy requirements, is controlled by the activity of glycogen phosphorylase. This enzyme exists in two states: phosphorylase b..is a form of low concentration... Under the action of phosphorylase kinase it is phosphorylated at one serine residue in each of the four subunits, to give the highly active phosphorylase a. |