| 释义 |
oxazolone Chem.|ɒkˈsæzələʊn|
[f. as prec. + -one.]
Any compound containing the nucleus obtained by hydrogenating one of the double bonds of oxazole and replacing a methylene group by a carbonyl group; = azlactone.
1899Japp & Findlay in Jrnl. Chem. Soc. LXXV. i. 1027 It occurred to us that, by substituting an α-hydroxy⁓acid for the α-keto-alcohol in the foregoing reaction, it might be possible to prepare oxazolones (ketodi⁓hydro-oxazoles). 1947Sci. News IV. 70 The synthesis of penicillin G starts with a benzyl oxazolone and with penicillinamine, and attempts to recombine them. 1968A. Albert Heterocyclic Chem. (ed. 2) vi. 290 Of the oxazolones, the 5-isomer..and its derivatives are the best known. 1968R. O. C. Norman Princ. Org. Synthesis xviii. 604 The oxazolones or azlactones, prepared by the dehydration of N-acyl-α-amino-acids, are employed in Erlenmeyer's synthesis of α-amino-acids. 1975Nature 13 Nov. 149/2 We have examined..the production of antiparasite antibodies and parameters of T-cell function (the response to phytohaemagglutinin (PHA) and oxazolone). |