| 释义 |
Metopirone Pharm.|mɛtəʊˈpɪrəʊn|
Also metopirone.
[f. 2-methyl-1,2-di(pyrid-3-yl)propan-1-one, the chemical name (see metyrapone), with alteration of y to i and insertion of o.]
A proprietary name for metyrapone.
1960Lancet 17 Dec. 1332/2 Metopirone is an 11 β-hydroxylase inhibitor which presumably prevents the production of aldosterone by the adrenal gland. 1961Trade Marks Jrnl. 8 Feb. 172/1 Metopirone... Pharmaceutical preparations and substances for human use and for veterinary use. CIBA Limited.., Basle, Switzerland. 1962Lancet 19 May 1041/2 The duration of the action of metopirone was investigated, in order to determine the best dosage schedule in tests of pituitary function. 1973Arch. Internat. de Pharmacodynamie et de Thérapie CCII. 93 Metopirone was found to provoke in normal, but not in adrenalectomized rats, a three-fold increase in blood sugar and a four-fold increase in plasma adrenaline. |