| 释义 |
methonium Pharm.|mɪˈθəʊnɪəm|
[f. meth- + -onium.]
Any of various polymethylene bistrimethylammonium cations, [(CH3)3N(CH2)xN(CH3)3]2+ (where x is an integer), or salts of these ions, some of which are used as ganglionic blocking agents in the treatment of hypertension.
[1949: cf. decamethonium, hexamethonium s.v. hexa-.] 1950Lancet 26 Aug. 353/1 (heading) ‘Medical sympathectomy’ in hypertension. A clinical study of methonium compounds. 1952Pharmacol. Rev. IV. 220 The name of ‘methonium’ compounds for the members of the polymethylene bistrimethylammonium series has been approved by the British Pharmacopoeia Commission, and it is under this name, preceded by the appropriate numerical prefix, that they are now known. 1969Jrnl. Neurochem. XVI. 1173 Some members of the methonium series are..taken up by a saturable mechanism and..the uptakes can be described quantitatively by Michaelis-Menten type kinetics. |