| 释义 |
ankyrin, n. Biochem.|ˈæŋkɪrɪn|
[f. Gr. ἄγκυρα (see anchor n.1) + -in1.]
A globular protein found on the inside of the plasma membrane in certain cells, which mediates the attachment of other proteins, esp. that of spectrin in mammalian red blood cells.
1975R. E. Stephens in Jrnl. Cell Biol. LXIV. 419/2 Because of the bifurcating nature and anchor-like function of ciliary rootlets, the generic name ankyrin, from the Greek ankyra (anchor) is proposed for these characteristic high molecular weight structural proteins of rootlets and rootlet-related organelles. 1984Holtzman & Novikoff Cells & Organelles (ed. 3) ii. xi. 287 Via ankyrin and other proteins, the actin-spectrin network is bound to some of the integral proteins of the plasma membrane. 1987Nature 6 Aug. 533/1 In several nonerythroid cell types..homologues of ankyrin and spectrin (fodrin) are localized in specific membrane domains. 1989B. Alberts et al. Molecular Biol. of Cell (ed. 2) vi. 289 By connecting band 3 protein to spectrin, ankyrin links the spectrin network to the membrane. |