| 释义 |
lincomycin Pharm.|lɪŋkəʊˈmaɪsɪn|
[f. mod.L. linco(lnensis, specific epithet (see def.) + -mycin.]
An antibiotic, C18H34N2O6S, produced by cultures of the bacterium Streptomyces lincolnensis var. lincolnensis and given orally or by injection (usu. as the hydrate of the hydrochloride) to combat various Gram-positive bacteria, esp. staphylococci and streptococci.
1963Bacteriol. Proc. 1963 94/1 Lincomycin, developed by The Upjohn Co., is a new antibiotic, chemically distinct from others now in use. 1966Practitioner July 90 Lincomycin hydrochloride should prove useful in general practice against the common gram-positive infections. 1969New Scientist 8 May 277/1 The group A haemolytic streptococci..are becoming increasingly resistant to tetracycline, erythromycin, and lincomycin. 1973Brit. Pharmacopœia 1973 266/2 Lincomycin Hydrochloride is the monohydrate of the hydrochloride of methyl 6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-d-erythro-d-galacto-octapyranoside. 1975Daily Colonist (Victoria, B.C.) 31 Jan. 3/6 Lee Smith said..that United States reports on the drugs clindamycin and lincomycin..were ‘wildly exaggerated’ in the news media. |