| 释义 |
ancrod, n. Pharm.|ˈæŋkrɒd|
[Prob. f. mod.L. Agk(ist)rod(on (coined by A. M. F. J. Palisot de Beauvois 1799, in Trans. Amer. Philos. Soc. IV. 381), lit. ‘barb-tooth’, f. Gr. ἄγκιστρον fish-hook + ὀδούς, ὀδοντ-tooth, former genus name of the snake from which the enzyme is obtained, with alteration of -gk- to -nc- following the usual model for Gr. transliteration.]
An anticoagulant protease that lowers the concentration of fibrinogen by cleaving fibrin in the blood, and is given intravenously in the treatment and prevention of some kinds of thrombosis.
1970Brit. Med. Jrnl. 5 Dec. 591/1 The defibrinating agent ancrod (Arvin) was used instead of Leparin for intermediate haemodialysis. 1977Lancet 19 Mar. 625/1 Fifteen patients with severe intermittent claudication were treated by therapeutic defibrination with subcutaneous injections of ancrod for 5 weeks. 1984New Scientist 25 Oct. 43/1 Ancrod, an anticoagulant derived from the Malayan pit viper. |