| 释义 |
isatoic, a. Chem.|aɪsəˈtəʊɪk|
[See below.]
1. isatoic acid [tr. G. isatosäure (H. Kolbe 1884, in Jrnl. f. prakt. Chem. XXX. 85): see isat-].
†a. = isatoic anhydride (below). Obs.
b. N-Carboxyanthranilic acid, C6H4(COOH) (NHCOOH), known only as its derivatives.
1885Jrnl. Chem. Soc. XLVIII. i. 58 Isatin is converted by chromic acid, dissolved in glacial acetic acid, into an acid which the author styles isatoic acid... It is sparingly soluble in cold water and alcohol. Ibid. 666 Anthranil⁓carboxylic acid..has the same composition as isatoic acid. 1899[see sense 2]. 1930Chem. Abstr. XXIV. 4793 Isatoic acid and its derivs. are obtained by treating congo acid solns. of aromatic o-aminocarboxylic acids with COCl2.
2. isatoic anhydride [after G. isatosäure-anhydrid (E. Erdmann 1889, in Ber. d. Deut. Chem. Ges. XXXII. 2163)]. The anhydride, C6H4·CO·O·CO·NH, of isatoic acid, obtained by oxidation of isatin.
1899Jrnl. Chem. Soc. LXXVI. i. 939 ‘Isatoic acid’ is thus not an acid, but the anhydride of a dicarboxylic acid, COOH·C6H4·NH·COOH. The author calls this dibasic acid isatoic acid, and the anhydride, previously known as isatoic acid he terms isatoic anhydride. 1944Jrnl. Org. Chem. IX. 55 Isatoic anhydride is a convenient reagent for certain anthranoylations. 1971Jrnl. Pharmaceutical Sci. LX. 1252/1 The condensation of isatoic anhydride with primary amines was found to yield the corresponding substituted anthranilamides. |