| 释义 |
progestin Physiol.|prəʊˈdʒɛstɪn|
[f. pro-1 5 + gestation + -in1.]
a. Progesterone, esp. an unpurified preparation of it.
b. = progestogen, gestagen.
1930W. M. Allen in Amer. Jrnl. Physiol. XCII. 174 We have as yet proposed no name for this hormone of the corpus luteum... In so far as we are acquainted with its physiological behavior, its chief action lies in its ability, by alteration of the endometrium, to aid gestation in the castrated rabbit; and for this reason we wish to propose for it the name progestin, i.e., a substance which favors gestation. 1935[see androsterone]. 1935W. M. Allen et al. in Nature 24 Aug. 303/2 Heretofore, two different names have been used in the literature for this hormone (progestin, luteosterone). For the sake of international uniformity, we agree to use..the name progesterone for the pure hormone. 1936Jrnl. Amer. Med. Assoc. 23 May 1809/1 The Council adopted the following terms: (1) progesterone to indicate the chemically pure substance..(2) progestin as a general term to indicate the substance (and other chemically allied substances..in case any such compounds are subsequently discovered) without reference to the state of chemical purity. 1944J. Hoffman Female Endocrinol. xli. 711 The term progestin is applied to crude extracts of corpus luteum tissue which possess progestational activity. The name progesterone describes the crystalline form of the luteal hormone. 1945H. Burrows Biol. Actions of Sex Hormones xxi. 389 More than one substance having the same kind of action as progesterone is known, and a generic name is therefore convenient. The author has used the term ‘progestin’ to denote chemical compounds having a biological action comparable with that of progesterone. [Note] ‘Progestogen’ has been suggested as an alternative generic name. Ibid. 390 The corpora lutea of the ovary are the chief natural source of progestin... The placenta is another source. 1961J. Rock in C. A. Villee Control of Ovulation xii. 228 The two artificial steroids are called ‘progestins’ because of the fact that their action resembles that of progesterone. 1966New Scientist 15 Dec. 620/1 The synthetic progestins which are contained in all oral contraceptive tablets were in fact introduced for the wrong reason. 1976Sci. Amer. Feb. 32/2 The steroid hormones..include the male sex hormones (collectively called the androgens), the female sex hormones (the estrogens and the progestins) and the hormones secreted by the cortex. |