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单词 ubiquitinate
释义 ubiquitinate, v.
Brit. |juːˈbɪkwɪtɪneɪt|, |jʊˈbɪkwɪtɪneɪt|, U.S. |juˈbɪkwətnˌeɪt|
[‹ ubiquitin n. + -ate suffix3 Compare slightly earlier ubiquitinated adj., ubiquitination n.]
trans. To bind ubiquitin to (a protein). Usu. in pass.
1983Science 29 July 469/1 H2A.X is ubiquitinated, phosphorylated, and acetylated like the major H2A variants.1996Science 15 Nov. 1199 The initiation of anaphase and exit from mitosis require the activation of a proteolytic system that ubiquitinates and degrades cyclin B.2007D. Rutkowski & V. Lingappa in B. Lewin et al. Cells iii. 125 Translocated proteins can be exported to the cytosol, where they are ubiquitinated and degraded by the proteasome.
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