| 释义 |
tumorigenic, a. Med.|tjuːmərɪˈdʒɛnɪk|
Also tumo(u)r(o)-.
[f. tumour, tumor + -i-, -o + -genic.]
Capable of causing tumours.
1948Cancer Res. VIII. 410/1 It is thought that they [sc. these observations] afford an example of the tumorigenic action of..follicle-stimulating hormone. 1965Dissertation Abstr. XXVI. 1300/2 (heading) The salivary gland chromosomes of a tumorgenic strain of Drosophila melanogaster. 1971New Scientist 24 June 732/2 Tumourgenic hybrids had 80 chromosomes instead of the expected 116. 1979Nature 11 Oct. 486/1 The significance of EBV [sc. a virus] as a tumorigenic agent in humans could be finally established if it were possible to prevent tumours by vaccination. 1980Ibid. 21 Feb. 777/1 The present experiments show that human diploid cells can be transformed in vitro into tumorogenic cells by X-ray-irradiation.
So ˈtumorigen (and varr.), a tumorigenic agent; tumoriˈgenesis, the production or formation of a tumour; ˌtumorigeˈnicity, tumorigenic property.
1948Cancer Res. VIII. 397 (heading) Hormonal imbalances in tumorigenesis. 1952J. E. Gregory Pathogenesis of Cancer (ed. 2) xii. 147 These elements [sc. coal tar, etc.] are called carcinogens. We now know that if the virus was present cancer would develop, but if it was not present only benign tumors and hyperplasia would develop as a result of the irritation. This latter fact makes it appear that a better name for these substances might have been tumorgens, instead of carcinogens. 1967New Scientist 25 May 478/2 More than 50 per cent of the tumorigenicity of 24-hour condensate..was due to stable, non-volatile carcinogens. 1970McGraw-Hill Yearbk. Sci. & Technol. 217/2 Other studies have shown..the dominance of tumorogenicity, and the characteristics of polyoma transformation in hybrids between transformed and nontransformed cells. 1971Nature 17 Sept. 195/1 Irradiated hamster foetal cells protect male hamsters against SV40 tumorigenesis. 1978Brit. Med. Jrnl. 11 Mar. 649/2 It would be a disservice to the public to allow marketing of a compound which is a demonstrated tumorigen. 1980European Jrnl. Cell Biol. XXII. 491 The tumorgenicities of RBCF-1 cells. |