| 释义 |
frusemide, n. Pharm.|ˈfruːsəmaɪd|
Also (chiefly U.S.) furosemide, (in early use) fursemide.
[f. furyl n. (subsequently rearranged as fru-) + sem-, of unknown origin + -ide.]
A potent diuretic drug, C12H11ClN2O5S , used esp. in the treatment of oedema; 4-chloro-N-furfuryl-5-sulphamoylanthranilic acid.
1963Jrnl. Amer. Med. Assoc. 18 May 576/2 (table) Nonproprietary name, fursemide. 1964Ibid. 20 July 227/1 Nonproprietary name, furosemide... Note: Fursemide was the former nonproprietary name for this compound. 1964Lancet 21 Nov. 1085/2 Frusemide (‘Lasix’)..contains the same sulphamoylbenzene grouping as chlorothiazide and chlorthalidone... Nevertheless, preliminary data available when the drug was offered for clinical trial in Great Britain (under the name of furosemide) suggested that it differed in action from the thiazides. 1971D. Lambert in C. Bonington Annapurna South Face App. G. 296 Singh found that in over 400 cases of mountain sickness in unacclimatized soldiers..considerable improvement resulted from administering frusemide, better known by its trade name Lasix. 1977Lancet 23 Apr. 910/1 She..was given several drugs for her respiratory problem including aminophylline..,frusemide (furosemide), and nitroglycerine. 1989Collier & Longmore Oxf. Handbk. Clin. Specialties (ed. 2) iii. 224 Treat heart failure in babies with nasogastric feeds, sitting upright, O2 , frusemide eg 1mg/kg/24h IV and digoxin 10µg/kg/24h PO. |