| 释义 |
finasteride, n. Pharmacol.
Brit. |fɪˈnastərʌɪd|, U.S. |fəˈnæstəˌraɪd|
[‹ a first element of unknown origin + ster- (in steroid n.) + -ide suffix.]
A drug that inhibits the conversion of testosterone to the more potent dihydrotesterone in the human prostate gland and hair follicles, used in the treatment of benign prostatic hyperplasia and male-pattern baldness.
Chemical name: N-tert-butyl-3-oxo-4-aza-5α-androst-1-ene-17β-carbamate.
1989Pharmaceut. Business News 4 Aug. 23/2 MK-906 (Proscar), the 5-alpha reductase inhibitor for use in benign prostatic hyperplasia has been designated finasteride. 1998Nature 5 Feb. 537/1 Only two treatments have been sanctioned by the US Food and Drug Administration... The other is finasteride (sold as Propecia by Merck & Co.), which is a reduced dosage of a prostate medication that inhibits production of dihydrotestosterone. 2003C. Wanjek Bad Med. 48 Finasteride entered the arena in the 1990s, marketed as a pill called Propecia... Taken orally, these pills retain hair that would have been lost by inhibiting an enzyme responsible for balding. |