| 释义 |
fenfluramine, n. Pharmacol.
Brit. |fɛnˈflʊərəmiːn|, U.S. |fɛnˈflʊrəˌmin|
[‹ fen- (representing phen- comb. form) + flur- (alteration of fluoro- comb. form) + amine n., elements of the systematic name. Compare French phenfluoramine (1964).]
A drug structurally related to amphetamines but causing less stimulation of the central nervous system, formerly used clinically as an appetite suppressant but withdrawn because of toxicity. Cf. fen-phen n.
Chemical name: N-ethyl-α-methyl-3-trifluoromethyl phenethylamine, C12H16F3N.
1964Pharmaceut. Jrnl. 192114/1 Approved name... Fenfluramine. 1986Sci. Amer. Aug. 57 a/1 d-Fenfluramine leads to a decrease in stress-induced eating. 1995Guardian 5 Apr. ii. 8/4 My doctor prescribed me fenfluramine hydrochloride and wished me good luck in my pound-shedding endeavours. 1997J. Steingarten Man who ate Everything (1998) ii. 95 An experimental combination of two commonly used appetite drugs, fenfluramine and phentermine, was shown to produce very impressive weight loss. 2002Independent 15 Mar. i. 7/1 It contained fenfluramine, an appetite suppressant that was subject to a global ban in 1997 after it was linked with heart and lung problems in some patients. |