| 释义 |
suramin Pharm.|ˈsɜːrəmɪn|
Also Suramin.
[Etym. unknown: perh. f. surra.]
A complex symmetric urea used in the treatment of trypanosomiasis and filariasis. Also suramin sodium.
1941Brit. Pharmacopœia 1932 Add. iv. 33 Suramin is the symmetrical urea of the sodium salt of m-benzoyl-m-amino-p-methylbenzoyl-1-aminonaphthalene-4:6:8-trisulphonic acid. 1951A. Grollman Pharmacol. & Therapeutics xx. 416 Atoxyl..was the first drug used successfully in trypanosomiasis. Tryparsamide..was an improvement and with Suramin..is effective in the treatment of the early stage of the disease before the organisms appear in the spinal fluid. 1974Encycl. Brit. Micropædia IX. 687/3 Suramin sodium, a white or pinkish powder soluble in water, is administered in an aqueous or saline solution. 1978Nature 22 June 627/1 Three antitrypanosomal drugs are listed by the WHO as essential for the treatment of human sleeping sickness caused by African trypanosomiasis. They are melarsoprol (Mel B), pentamidine (Lomidine) and suramin (Antrypol, Germanin). |