vicissitude /vi-sisˈi-tūd/

1. Change
2. Alternation
3. Mutation
4. Change of fortune (informal, for the worse)

vicissitūˈdinous adjective

• lay-bys
• lay by the heels
• lay claim to
• lay clerk
• lay clerks
• lay communion
• lay-day
• lay-days
• lay down
• lay-down
• lay down one's arms
• lay-downs
• lay down the law
• layer
• layer cake
• layered
• layering
• layerings
• layers
• layette
• layettes
• lay eyes on
• lay-figure
• lay-figures
• lay great store by