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WordReference Random House Unabridged Dictionary of American English © 2024Rh neg•a•tive (är′āch′ neg′ə tiv).USA pronunciation - PhysiologySee under Rh factor.
WordReference Random House Unabridged Dictionary of American English © 2024Rh fac•tor, (är′āch′ fak′tər),USA pronunciation [Physiol.]- Physiologyany of a type of specific antigen present on the surface of red blood cells, persons having inherited such antigens being designated Rh+ (Rh positive) and persons lacking them, a much smaller group, being designated Rh-(Rh negative): blood of Rh- persons is incompatible with Rh+ blood because of antibody reaction, and an Rh- woman who bears an Rh+ baby will have formed antibodies to the fetal blood that, unless removed from her bloodstream by apheresis in a subsequent pregnancy, will be carried across the placenta and destroy red blood cells of the next Rh+ fetus, resulting in erythroblastosis in the newborn.
- so called because first found in the blood of rhesus monkeys 1940–45
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