The Greeks had another word for such a character failing, which was hamartia, literally "fault," failure," or "guilt." The term tragic flaw, which originally was used strictly in a literary sense, is now commonly used to refer to anyone whose baser nature gets the better of them. Shakespeare's plays are full of such unfortunate people, perhaps most famously Othello — who, thanks to his rabid jealousy and a little misunderstanding about a handkerchief, ended up killing the love of his life.