take it out of sb
also take a lot out of sb— phrasal verb with take uk/teɪk/us/teɪk/verb took, taken
to make someone very tired:
Running around after 25 preschoolers takes it out of me by the end of the week.
英语词典包含110679条英英释义在线翻译词条，基本涵盖了全部常用单词的英英翻译及用法，是英语学习的有利工具。