unresponsive
adjective /ˌʌnrɪˈspɒnsɪv/
  /ˌʌnrɪˈspɑːnsɪv/
(formal)- not reacting to somebody/something; not giving the response that you would expect or hope for
- If the person is unconscious or unresponsive, dial 999.
 - unresponsive to something a politician who is unresponsive to the mood of the country
 - She is a cold, unfeeling and unresponsive woman.
 - This combination of symptoms seems to be unresponsive to conventional medical treatment.