► harmfulcausing harm, or likely to cause harm:  The harmful effects of smoking are well known. Wash the fruit to remove harmful bacteria.
► poisonous containing a substance that can kill you or make you sick if you eat it, breathe it, etc.:  She was bitten by a poisonous snake and had to go to the hospital.
► toxic poisonous. Used especially about chemicals:  Burning tires produces toxic fumes.
► damaging causing physical damage or harmful effects:  The researchers are studying the damaging effects of alcohol on the brain.
► detrimental formal harmful or damaging to something:  Fatty foods are detrimental to your health.
► destructive causing something to be destroyed:  A large population of deer can be very destructive to woodlands.
► deleterious formal damaging or harmful:  The treatment is supposed to reverse some of the deleterious effects of aging.