to give up one's job or position
to renounce (something) voluntarily, esp to relinquish (e.g. a right or position) by a formal act
(+ to) to reconcile (oneself) to an unpleasant fact, circumstance, etc
She resigned herself to her fate
resigner noun
[Middle English resignen via French from Latin resignare to unseal, cancel, from re- + signare: see sign2]