1. In large part; mainly or chiefly
   - largely, for the most part, predominately 
2. Usually; as a rule
   - by and large, generally, more often than not

See also: most

• Sideritis
• sideroblast
• sideroblastic anaemia
• sideroblastic anemia
• siderochrestic anaemia
• siderochrestic anemia
• siderocyte
• siderolite
• sideropenia
• siderophilin
• siderosis
• siderostat
• sidesaddle
• sideshow
• sideslip
• sidesman
• sidesplitter
• sidesplitting
• sidesplittingly
• sidestep
• sidestroke
• sideswipe
• sidetrack
• sidewalk
• sidewall