1. Unpleasantly
   "his ignorance was painfully obvious"
   - distressingly 
2. In or as if in pain
   "she moved painfully forward"
   - sorely

See also: painful

Antonym: painlessly

• Sorghum vulgare caudatum
• Sorghum vulgare rosburghii
• Sorghum vulgare technicum
• sorgo
• Soricidae
• sorites
• sororal
• sororicide
• optical telescope
• optically
• optician
• optics
• optimal
• optimally
• optimisation
• optimise
• optimism
• optimist
• optimistic
• optimistically
• optimization
• optimize
• optimum
• option
• optional