1. Toward the source or against the current
   - upstream

Antonym: downriver

• MDMA
• me
• mea culpa
• mead
• Mead's milkweed
• Meade
• meadow
• meadow beauty
• meadow bright
• meadow buttercup
• meadow clary
• meadow cranesbill
• meadow cress
• meadow fern
• meadow fescue
• meadow foxtail
• meadow goldenrod
• meadow jumping mouse
• meadow leek
• meadow lily
• meadow mouse
• meadow mushroom
• meadow pea
• meadow pipit
• meadow rue