1. A hereditary disorder of lipid metabolism occurring most frequently in individuals of Jewish descent in eastern Europe; accumulation of lipids in nervous tissue results in death in early childhood
   - Tay-Sachs disease, Sachs disease, infantile amaurotic idiocy

Type of: autosomal recessive defect, autosomal recessive disease, lipidosis, monogenic disease, monogenic disorder

Encyclopedia: Tay-Sachs

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