1. Causing debilitation
   - debilitative, enfeebling, weakening

1. Weaken mentally or morally 
2. Disturb the composure of
   - faze, unnerve, unsettle

See also: debilitating, enervation

Type of: discomfit, discompose, disconcert, untune, upset, weaken

• come into being
• come near
• come of age
• come off
• come off it
• come out
• come out of the closet
• come over
• come round
• come short
• come through
• come to
• come to grips
• come to hand
• come to life
• come to light
• come to mind
• come to terms with
• come to the fore
• come together
• come true
• come up
• come up to
• come upon
• come what may