1. Sufficiently significant to affect the whole world
   - earthshaking, world-shaking, world-shattering

See also: important, significant

• infant prodigy
• infant school
• infant's-breath
• infanta
• infante
• infanticide
• infantile
• infantile amaurotic idiocy
• infantile autism
• infantile fixation
• infantile paralysis
• infantilism
• infantine
• infantry
• infantryman
• infarct
• infarction
• infatuate
• infatuated
• infatuation
• infeasibility
• infeasible
• infect
• infected
• infection