1. A game of chance, played by betting on the outcome of two pennies thrown in the air

1. Having two people riding on a motorcycle

Encyclopedia: Two-up

• merestone
• up-to-the-minute
• Upanishad
• upas
• upbeat
• upbound
• upbraid
• upbraider
• upbraiding
• upbringing
• upcast
• upchuck
• upcoming
• upcountry
• upcurved
• update
• updating
• updation
• Updike
• updraft
• upend
• upended
• upending
• upfield
• upfront