1. Heavily burdened with work or cares
   "found himself loaded down with responsibilities"
   - bowed down, overburdened, weighed down 
2. Bearing a physically heavy weight or load
   "loaded down with packages"
   - burdened, heavy-laden

See also: burdened, encumbered

• restraint
• restraint of trade
• restrengthen
• restrict
• restricted
• restricting
• restriction
• restriction endonuclease
• restriction enzyme
• restriction fragment
• restriction nuclease
• restriction site
• restrictive
• restrictive clause
• restrictive covenant
• restrictively
• restrictiveness
• restring
• restroom
• type genus
• type I allergic reaction
• type I diabetes
• type II diabetes
• type IV allergic reaction
• type metal