1. In a manner that relieves fatigue and restores vitality
   "the air was refreshingly cool"
   - refreshfully 
2. In a pleasantly novel manner
   "she was refreshingly free from shyness"

See also: refreshing

• multifariousness
• multiflora
• multiflora rose
• multifocal IOL
• multifocal lens implant
• multifold
• multiform
• multilane
• multilateral
• multilaterally
• multilevel
• multilingual
• multimedia
• multimedia system
• multimeter
• multimillion
• multimillionaire
• multimodal
• multinational
• multinomial
• multinucleate
• multiparous
• multipartite
• multiparty
• multiphase