1. Exceedingly harmful
   - baneful, deadly, pernicious 
2. Likely to spread and cause an epidemic disease
   - pestilential, pestiferous, plaguey

See also: epidemic, noxious, pestilence

• make unnecessary
• make up one's mind
• make vibrant sounds
• make water
• make way
• make whoopee
• make-believe
• make-do
• make-peace
• make-work
• Makedonija
• makeover
• maker
• makeready
• makeshift
• makeup
• makeweight
• Makin
• making
• making known
• making love
• making water
• mako
• mako shark
• makomako