1. Extremely irritating to the nerves
   "the stressful days before a war"
   - nerve-racking, nerve-wracking, trying

See also: disagreeable

• plague
• plague pneumonia
• plague spot
• plaguey
• plaguily
• plaguy
• plaice
• plaid
• plain
• plain chocolate
• plain clothes
• plain flour
• plain sailing
• plain stitch
• plain turkey
• plain wanderer
• plain weave
• plain-woven
• plainchant
• plainclothesman
• plainly
• plainness
• Plains Indian
• plains lemon monarda
• plains pocket gopher