1. With desperation
   "'Why can't you understand?,' she asked despairingly"
   - despondently

See also: despairing

• presenile dementia
• present
• present moment
• present participle
• present perfect
• present perfect tense
• present progressive
• present progressive tense
• present tense
• present times
• present-day
• presentable
• presentably
• presentation
• presentational
• presentative
• presentee
• presenteeism
• presenter
• presentient
• presentiment
• presentism
• presentist
• presently
• presentment