long-lasting 
adjective
Enduring or having endured for a long period of time: long-lasting effects a long-lasting friendship...
- They suggest using a powder, applied with a fine but firm brush, for the most natural and long-lasting effect.
- A large number also suffer long-lasting psychological and emotional effects from being threatened or attacked.
- The infection causes severe itching but no long-lasting effects.
Synonyms
enduring, lasting, long-lived, long-running, long-established, long-standing, lifelong;
permanent, abiding, surviving, deep-rooted, established;
strong, durable, stable, fast, firm, reliable;
time-honoured, traditional