单词	hyperalgesia
释义	hyperalgesia /ˌhʌɪpəralˈdʒiːzɪə / noun [mass noun] Medicine Abnormally heightened sensitivity to pain.These mediators and the related tissue injury prolong pain and hyperalgesia.... They also act as mediators of inflammatory hyperalgesia. The mechanism for the pain may involve the development of an area of hyperalgesia as a result of myofascial stretch injury. Derivatives hyperalgesic adjective ... One hypothesis is that both the hyperalgesic and analgesic actions of isoflurane require noradrenergic pain pathways. Of particular interest to us recently have been the mechanisms by which these direct hyperalgesic mediators affect primary afferents to lower threshold. When H - 8, a protein kinase G inhibitor, was injected 90 minutes after PGE2, however, the hyperalgesic duration was reduced.
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