单词	leukotriene
释义	leukotriene /ˌluːkə(ʊ)ˈtrʌɪiːn / noun Biochemistry Any of a group of biologically active compounds, originally isolated from leucocytes. They are metabolites of arachidonic acid, containing three conjugated double bonds.Prostaglandins and leukotrienes from arachidonic acid metabolism are highly inflammatory molecules, and play an important role in the pathophysiology of asthma.... Arachidonic acid metabolites such as leukotrienes and thromboxanes have been shown to increase in the lung during ischemia-reperfusion injury in a dog model of warm ischemia. In addition to chemokines, lipid metabolites such as leukotrienes and prostaglandins are emerging as important upstream controllers of DC migration toward LNs.
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