soul-sick
/ˈsəʊlsɪk/adjective
1In religious contexts: that has a sick soul; suffering from spiritual or moral ill health. Now rare.
2Chiefly literary. Sick at heart; suffering from spiritual unease or distress; deeply dejected or depressed.
3Of a quality, condition, time, etc.: characterized by spiritual dejection or malaise.
noun
With the and plural concord. Soul-sick people collectively.
Origin
Mid 16th century. From soul + sick.