alteplase
/ˈaltəpleɪz/Medicine and Pharmacology
noun
A form of the enzyme plasminogen activator produced by genetic engineering and used to dissolve blood clots in thromboembolic disorders such as myocardial infarction, deep venous thrombosis, and pulmonary embolism.
- Alteplase is a form of the tissue-type of plasminogen activator, as opposed to the urokinase-type. It is produced by a line of Chinese hamster ovary cells transformed with the human tissue-type plasminogen activator gene..
Origin
1980s; earliest use found in PR Newswire. From al- of unknown origin + t- and -e + pl- + -ase.
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