释义 |
physostigmine /ˌfʌɪsəʊˈstɪɡmiːn /noun [mass noun] ChemistryA compound which is the active ingredient of the Calabar bean and is used medicinally in eye drops on account of its anticholinesterase activity.- A tricyclic alkaloid; chemical formula: C15H21N3O2.
Julian was interested in medicinal plants, particularly the Calabar bean whose active principle, physostigmine, was first isolated by the German chemists Jobst and Hesse in 1864....- The symptoms of anticholinergic overdose may be treated with physostigmine in a dosage of 1 to 2 mg given intramuscularly or intravenously at 20-minute intervals.
- But since physostigmine could be isolated only from the Calabar bean, the drug was not readily available.
Origin Mid 19th century: from the modern Latin genus name Physostigma (to which the Calabar bean belongs) + -ine4. |