phalloidin
/faˈlɔɪdɪn
/noun [mass noun] Chemistry
The toxin present in the death cap toadstool. It is a peptide with seven amino acids in a ring structure bridged by a sulphur atom.We show here that photosensitization with BAYy 3118 induces an immediate loss of actin reactivity with phalloidin, a toxin that specifically forms tight complexes with polymerized F - actin....
- However, since phalloidin stabilizes F-actin structure and virtually abolishes the dissociation of actin monomers from filament ends, it also inhibits the dynamic behavior of actin filaments.
- Egg chambers were stained with Alexa 488-labeled phalloidin to reveal actin-rich structures (blue).
Origin
1930s: from modern Latin phalloides, specific epithet of the death cap toadstool Amanita phalloides (based on Greek phallos 'phallus') + -in1.