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单词 adrenoleukodystrophy
释义

adrenoleukodystrophy

/əˌdriːnə(ʊ)ˌluːkəʊˈdɪstrəfi/
(also adrenoleucodystrophy) Medicine
noun
Originally: an inherited (X-linked recessive) disorder characterized by atrophy of the adrenal cortex and degeneration of the white matter of the nervous system, typically appearing in prepubertal boys, and leading to Addisonian symptoms, spastic paralysis, and mental deterioration. Later also (more fully neonatal adrenoleukodystrophy): a similar disorder inherited in an autosomal recessive manner and appearing in infancy.
  • Both forms of adrenoleukodystrophy are associated with an inability to break down very long chain fatty acids, leading to their accumulation in body tissues..

Origin

1970s. From adreno- + leukodystrophy.

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更新时间:2025/2/23 4:32:57