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单词 penetrance
释义

penetrance

/ˈpɛnɪtr(ə)ns /
noun [mass noun] Genetics
The extent to which a particular gene or set of genes is expressed in the phenotypes of individuals carrying it, measured by the proportion of carriers showing the characteristic phenotype.Because of reduced penetrance, individuals of different genotypes can have the same phenotype....
  • With the exception of the relatively rare high penetrance, single gene disorders, genetic tests differ little from most other medical tests, providing evidence of statistical risk only.
  • High penetrance susceptibility genes probably account for no more than 5-10% of cases.

Origin

1930s: from German Penetranz.

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更新时间:2025/2/23 9:56:11