单词	acylate
释义	acylate /ˈeɪsʌɪleɪt / /ˈasɪleɪt/ verb [with object] Chemistry Introduce an acyl group into (a molecule or compound): (as adjective acylated) an acylated glycine derivative... The series of reactions begin in the cytosol where fatty acids are acylated by combining with coenzyme A, a derivative of the vitamin B5, also known as pantothenic acid. A recent investigation showed that acylated proteins found in lipid rafts were displaced due to the incorporation of eicosapentaenoic acid in Jurkat T cells. After evaporating excess reagent, the residue was acylated for 10 min at 150°C using 120 mm heptafluorobutyric anhydride. Derivatives acylation /eɪsʌɪˈleɪʃ(ə)n/ /asʌɪˈleɪʃ(ə)n/ noun ... Chain perdeuterated dimyristoylphosphatidylcholine was synthesized from perdeuterated myristic acid by acylation of glycerophosphocholine, as described previously. These reactions occur via acylation or alkylation and are often rapid, forming stable primary amide or secondary amine bonds. Besides prolonging receptor-peptide interactions, acylation is found not to abolish peptide conformational flexibility and it only moderately affects the bilayer elastic properties.
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